Intervention Studies for the metabolite 1-methyluric acid with food phytochemical Caffeine
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications |
|---|
Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caffeine | 1-methyluric acid | Human | Urine | Host metabolism | NoDoz® caplets + 180 mL water | pure compound | 15 | 200 mg | Single | 12,25 | 24.5mg±9 (0-24 (SD) (h)) | Publications | |||||||||
| Caffeine | 1-methyluric acid | Human | Urine | Host metabolism | gelatin capsules with water | pure compound | 107 | Healthy; 52 M; 55 F; Age= 22 ± 3 y; Spanish | 300 mg | Single | 16,49±0,84 (SEM) | Publications | |||||||||
| Caffeine | 1-methyluric acid | Human | Urine | Host metabolism | pure compound | 5 | Healthy; 4 F; 1 M; Nonsmokers; Age= 25±1 y | 0,004 g/Kg bw | Single | 12,30±2,4 (SEM) | Publications | ||||||||||
| Caffeine | 1-methyluric acid | Human | Urine | Host metabolism | 70 mL of acqueous solution | pure compound | 4 | Healthy;M; Age= 26-36 y | 350 mg | Single | 43,60±4,6 (SEM) | Publications | |||||||||
| Caffeine | 1-methyluric acid | Human | Urine | Host metabolism | dissolved in 200 mL water | pure compound | 7 | Healthy; age 22.2±4.0 y; caucasians | 0,005 g/Kg bw | Single | 22,05±4,69 (SD) | Publications | |||||||||
| Caffeine | 1-methyluric acid | Human | Urine | Host metabolism | dissolved in water | pure compound | 68 | Healthy; 35 M; 33 F; Age= 26.6 y ; 42 Caucasians; 26 Oriental | 300 mg | Single | 11,80±5 (SD) | Publications | |||||||||
| Caffeine | 1-methyluric acid | Human | Urine | Host metabolism | pure compound | 5 | Healthy; 4 F; 1 M; Smokers; Age= 30±9 y | 0,004 g/Kg bw | Single | 19,20±6,9 (SEM) | Publications | ||||||||||
| Caffeine | 1-methyluric acid | Human | Urine | Host metabolism | dissolved in 200 mL water | pure compound | 5 | Healthy; Age= 69.6±2.3 y; caucasians | 0,005 g/Kg bw | Single | 38,12±14,23 (SD) | Publications | |||||||||
| Caffeine | 1-methyluric acid | Human | Urine | Host metabolism | tablets | pure compound | 8 | Healthy; M; Age= 27 y | 200 mg | Single | 10,00 | Publications |