Intervention Studies for the metabolite 5-acetylamino-6-formylamino-3-methyluracil with food phytochemical Caffeine
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caffeine | 5-acetylamino-6-formylamino-3-methyluracil | Human | Urine | Host metabolism | pure compound | 5 | Healthy; 4 F; 1 M; Nonsmokers; Age= 25±1 y | 0,004 g/Kg bw | Single | 8,50±1,8 (SEM) | Publications | ||||||||||
| Caffeine | 5-acetylamino-6-formylamino-3-methyluracil | Human | Urine | Host metabolism | dissolved in water | pure compound | 68 | Healthy; 35 M; 33 F; Age= 26.6 y ; 42 Caucasians; 26 Oriental | 300 mg | Single | 4,30±3,4 (SD) | Publications | |||||||||
| Caffeine | 5-acetylamino-6-formylamino-3-methyluracil | Human | Urine | Host metabolism | pure compound | 5 | Healthy; 4 F; 1 M; Smokers; Age= 30±9 y | 0,004 g/Kg bw | Single | 12,30±7,6 (SEM) | Publications | ||||||||||
| Caffeine | 5-acetylamino-6-formylamino-3-methyluracil | Human | Urine | Host metabolism | tablets | pure compound | 8 | Healthy; M; Age= 27 y | 200 mg | Single | 4,40 | Publications |