Intervention Studies for the metabolite 1-methyluric acid with food phytochemical Theophylline
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Theophylline | 1-methyluric acid | Human | Urine | Host metabolism | tablets with 100 mL water | pure compound | 3 | Healthy; 2 M; 1 F; Age= 25.7±1.2 y | 375 mg | Single | 16,70±1,8 (SD) | Publications | |||||||||
| Theophylline | 1-methyluric acid | Human | Urine | Host metabolism | with 100 mL water | pure compound | 4 | Healthy; 3 F; 1 M; Age= 24-33 y | 375 mg | Single | 17,80±1,9 (SD) | Publications | |||||||||
| Theophylline | 1-methyluric acid | Human | Urine | Host metabolism | 15 mL elixir | pure compound | 6 | Healthy; M; Age= 24±1.06 y | 500 mg | Single | 19,70±1,9 (SD) | Publications | |||||||||
| Theophylline | 1-methyluric acid | Human | Urine | Host metabolism | 15 mL elixir | pure compound | 6 | Healthy; M; Age= 24±1.06 y | 250 mg | Single | 25,30±2,3 (SD) | Publications | |||||||||
| Theophylline | 1-methyluric acid | Human | Urine | Host metabolism | 15 mL elixir | pure compound | 6 | Healthy; M; Age= 24±1.06 y | 375 mg | Single | 23,20±3,3 (SD) | Publications | |||||||||
| Theophylline | 1-methyluric acid | Human | Urine | Host metabolism | dissolved in 100 mL water | pure compound | 9 | Healthy; M; Age= 31.1 y | 200 mg | Single | 21,70±5,9 (SD) | Publications |