Intervention Studies for the metabolite 3-methylxanthine with food phytochemical Theophylline
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Theophylline | 3-methylxanthine | Human | Urine | Host metabolism | dissolved in 100 mL water | pure compound | 9 | Healthy; M; Age= 31.1 y | 200 mg | Single | 7,00±0,9 (SD) | Publications | |||||||||
| Theophylline | 3-methylxanthine | Human | Urine | Host metabolism | with 100 mL water | pure compound | 4 | Healthy; 3 F; 1 M; Age= 24-33 y | 375 mg | Single | 12,00±1,3 (SD) | Publications | |||||||||
| Theophylline | 3-methylxanthine | Human | Urine | Host metabolism | 15 mL elixir | pure compound | 6 | Healthy; M; Age= 24±1.06 y | 250 mg | Single | 17,80±1,4 (SD) | Publications | |||||||||
| Theophylline | 3-methylxanthine | Human | Urine | Host metabolism | tablets with 100 mL water | pure compound | 3 | Healthy; 2 M; 1 F; Age= 25.7±1.2 y | 375 mg | Single | 10,40±1,9 (SD) | Publications | |||||||||
| Theophylline | 3-methylxanthine | Human | Urine | Host metabolism | 15 mL elixir | pure compound | 6 | Healthy; M; Age= 24±1.06 y | 500 mg | Single | 12,90±2,1 (SD) | Publications | |||||||||
| Theophylline | 3-methylxanthine | Human | Urine | Host metabolism | 15 mL elixir | pure compound | 6 | Healthy; M; Age= 24±1.06 y | 375 mg | Single | 15,70±2,2 (SD) | Publications |