Intervention Studies for the metabolite Urolithin B-3-glucuronide with food phytochemical Ellagic acid
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ellagic acid | Urolithin B-3-glucuronide | Human | Urine | Gut microbiota metabolite | Grumixama juice | Food | 10 | Healthy;10F;Age=29.33 ± 7.73; BMI=23.05 ± 2.93 kg/m² | 10 mL kg−1 body weigh ml | Single | 24 h | Publications | |||||||||
| Ellagic acid | Urolithin B-3-glucuronide | Human | Urine | Gut microbiota metabolite | Jabuticaba dessert ( 20g of jabuticaba peel and seed powder) | Food | 35 | Healthy; 18M;17F; Age=29.2 ± 6.4 | Single | 48 h | 24-36 | Publications | |||||||||
| Ellagic acid | Urolithin B-3-glucuronide | Human | Urine | Gut microbiota metabolite | 300 ml of non-clarified cagaita Juice ( 70mg of Ellagic acid) | Food | 16 | Healthy;4M;12F;Age=33 ± 7; BMI=23 ± 3 | 300ml | Single | 24 h | 24 | Publications | ||||||||
| Ellagic acid | Urolithin B-3-glucuronide | Human | Plasma | Gut microbiota metabolite | Strawberry juice (12g OF Freeze-dried strawberry) | Food | 38 | Healthy; Age= 66.7 ± 4.4;BMI=23.8 ± 2.4 kg/m² | Chronic | 45- 90 days | 45 days | 645.8-828.0±493.2 - 505.9 (SD) | Publications | ||||||||
| Ellagic acid | Urolithin B-3-glucuronide | Human | Urine | Gut microbiota metabolite | Pomegranate extract (210 mg of Ellagic acid) | Extract | 49 | Healthy; 32M;17F;Age=40-65; BMI= >27 kg/m² | 210mg | 3 doses | 24 h | Publications | |||||||||
| Ellagic acid | Urolithin B-3-glucuronide | Human | Urine | Gut microbiota metabolite | 30 g of peeled walnuts (457.3 mg of ellagic acid) | Food | 20 | Healthy; 11M;9F;Age=21-55; BMI= <25 kg/m² | 30g | 3 doses | 24 h | Publications |