Intervention Studies for the metabolite Curcumin sulfate with food phytochemical Curcumin
Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Curcumin | Curcumin sulfate | Human | Plasma | Host metabolism | 500 mg of Cureit™ in capsule with 240 mL water | pure compound | 15 | Healthy, BMI 18.5-24.9 kg/m2 | 232,5 mg | Single | 2,25 | 1,06 | 0,9 | (0-24h) | 0,3 | Publications | |||||
Curcumin | Curcumin sulfate | Human | Plasma | Host metabolism | liquid droplet micromicellar formulation (400 mg) | pure compound | 12 | Healthy, 6 M/6 F, age M (28.7 ± 7.7 y), age F (29.8 ± 6.7 y). BMI M (24.8 ± 3.1 kg/m2), BMI F (23.6 ± 3.4 kg/m2) | 76 mg | Single | 1,6±0,08 (SEM) | 20,0 | 0,18 | Publications | |||||||
Curcumin | Curcumin sulfate | Human | Plasma | Host metabolism | unformulated 95% curcumin capsules (400 mg) | pure compound | 12 | Healthy, 6 M/6 F, age M (28.7 ± 7.7 y), age F (29.8 ± 6.7 y). BMI M (24.8 ± 3.1 kg/m2), BMI F (23.6 ± 3.4 kg/m2) | 380 mg | Single | 4±1,32 (SEM) | 1,0 | 1,9 | Publications |