Intervention Studies for the metabolite 5-(4'-hydroxyphenyl)-gamma-valerolactone-3'-sulfate with food phytochemical (-)-Epicatechin
Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
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(-)-Epicatechin | 5-(4'-hydroxyphenyl)-gamma-valerolactone-3'-sulfate | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 50 mL of solution + 60 mg of 14C-Epicatechin | Pure compound | 8 | Healthy; 8 M; Age=31±3; BMI=24.5±3.3 kg/m2 | 207 µmol | Single | 6,4±1 (SEM) | 272±56 (SEM) | 6,30±1,7 (SEM) | 18,35748792 | 38.0±4,7 µmol (SEM) ((0-48h)) | Publications |