Intervention Studies for the metabolite Phloretin-2'-glucuronide with food phytochemical Apple dihydrochalcones
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Apple dihydrochalcones | Phloretin-2'-glucuronide | Human | Plasma; Urine; Illeal fluid | Host metabolism | 500 mL of Thatchers Redstreak cider | food | 9 | Healthy; Age= 21-24 Y; BMI: 26.1 kg/m² | 46±0.3 μmol DHC µmol | Single | 24h | 0.6±0.1 (SD) | 73±11 (SEM) | 4.2 | 1933±354 nmol (SD) (0-24h) | Publications | |||||
| Apple dihydrochalcones | Phloretin-2'-glucuronide | Human | Urine | Host metabolism | 500 mL of Thatchers Redstreak cider | food | 5 | Ilestomy; Age= 40 - 54 ; BMI= 26 | 46±0.3 μmol DHC µmol | Single | 24h | 4.42 | 2026±186 nmol (SD) (0-24h) | Publications |