Intervention Studies for the metabolite Naringenin with food phytochemical Naringenin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Naringenin | Naringenin | Human | Plasma | Unchanged | 500 g Tomato/ 70 kg Bw | food | 41 | Healthy; 19M; 21F; Age= 28 ± 11 ; BMI= 23.3 ±3.8 Kg/m² | 3.4x10^-5 g flavanones ( 3.4x10-4 g naringenin/ kg BW; 6.14x10-7g naringenin-glucoside/ kg BW ) g/Kg bw | Single | 1.4±1.8 (SD) | 15.4±5.7 (SD) | 185.4 | 0-24h | Publications | ||||||
| Naringenin | Naringenin | Human | Plasma | Unchanged | 250 g tomato sauce /70 kg Bw | food | 41 | Healthy; 19M; 21F; Age= 28 ± 11 ; BMI= 23.3 ±3.8 Kg/m² | 2.4x10-5g flavanones/kg BW ( 2.3*10^-5 g naringenin/ kg BW ; 9,28*10-7g naringenin-glucoside/ kg BW) g/Kg bw | Single | 0.5±0.2 (SD) | 21.7±17.4 (SD) | 212.9 | 0-24h | Publications | ||||||
| Naringenin | Naringenin | Human | Urine | Unchanged | 500 g of tomato | food | 8 | Healthy; 4M;4F; Age=27-46; BMI=23 ±0.93 kg/m² | 0.252 of naringenin mg | Single | 9 nmol (SD) (0-24h) | Publications | |||||||||
| Naringenin | Naringenin | Human | Plasma and Urine | Unchanged | 250g of tomato sauce | food | 8 | Healthy; 4M;4F; Age=27-46; BMI=23 ±0.93 kg/m² | 0.868 mg of flavanones : [Naringenin] =0.8465 mg [Naringenin-7-glucoside] = 0.054 mg | Single | 0.31±0.06 (SD) | 11.9±2.7 (SD) | 979 | 0-∞ | 141.1 nmol (SD) (0-24h) | Publications | |||||
| Naringenin | Naringenin | Human | Plasma and Urine | Unchanged | 1 capsule (135 mg Hesperetin; 135 mg Naringenin) | pure compound | 6 | Healthy; 5M;1F; Age=25±3.9 ; BW=69.17±10.91 kg | 135 mg | Single | 3.67±0.82 (SD) | 2009.51±770.82 (SD) | 9424.52 | 0-∞ | 5.81 | 7.85 mg (0-24h) | Publications | ||||
| Naringenin | Naringenin | Human | Plasma | Unchanged | 500 g Tomato/ 70 kg Bw | food | 41 | Healthy; 19M; 21F; Age= 28 ± 11 ; BMI= 23.3 ±3.8 Kg/m² | 3.4x10^-5 g flavanones ( 3.4x10-4 g naringenin/ kg BW; 6.14x10-7g naringenin-glucoside/ kg BW ) g/Kg bw | Single | 1.4±1.8 (SD) | 15.4±5.7 (SD) | 185.4 | 0-24h | Publications | ||||||
| Naringenin | Naringenin | Human | Plasma | Unchanged | 250 g tomato sauce /70 kg Bw | food | 41 | Healthy; 19M; 21F; Age= 28 ± 11 ; BMI= 23.3 ±3.8 Kg/m² | 2.4x10-5g flavanones/kg BW ( 2.3*10^-5 g naringenin/ kg BW ; 9,28*10-7g naringenin-glucoside/ kg BW) g/Kg bw | Single | 0.5±0.2 (SD) | 21.7±17.4 (SD) | 212.9 | 0-24h | Publications | ||||||
| Naringenin | Naringenin | Human | Plasma; Urine | Unchanged | 1 capsule (135 mg Hesperetin; 135 mg Naringenin) | pure compound | 6 | Healthy; 5M;1F; Age=25±3.9 ; BW=69.17±10.91 kg | 135 mg | Single | 3,67±0,82 (SD) | 2009,51±770,82 (SD) | 9424,52 | 0-∞ | 5,81 | 7.85 mg (0-24h) | Publications | ||||
| Naringenin | Naringenin | Human | Plasma; Urine | Unchanged | 250g of tomato sauce | food | 8 | Healthy; 4M;4F; Age=27-46; BMI=23 ±0.93 kg/m² | 0.868 mg of flavanones : [Naringenin] =0.8465 mg [Naringenin-7-glucoside] = 0.054 mg | Single | 0,31±0,06 (SD) | 11,9±2,7 (SD) | 979 | 0-∞ | 141.1±38,6 nmol (SD) (0-24h) | Publications | |||||
| Naringenin | Naringenin | Human | Urine | Unchanged | 500 g of tomato | food | 8 | Healthy; 4M;4F; Age=27-46; BMI=23 ±0.93 kg/m² | 0.252 of naringenin mg | Single | 9±1,4 nmol (SD) (0-24h) | Publications |