Intervention Studies for the metabolite Glycyrrhetinic acid with food phytochemical Glycyrrhizin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Glycyrrhizin | Glycyrrhetinic acid | Human | Plasma | Gut microbiota metabolite | Glycyrrhizin capsules | pure compound | 20 | Healthy;M | 50 mg | Single | 12.9±1.8 (SD) | 68±37.2 (SD) | 1018 | 0-48h | 8.8±2.3 (SD) | Publications | |||||
| Glycyrrhizin | Glycyrrhetinic acid | Human | Plasma | Gut microbiota metabolite | Glycyrrhizin capsules | pure compound | 6 | Healthy; M; Age= 29.8± 3.1 ; BW=61±3.9 kg, H= 172.1±3.7cm | 75 mg | Single | 10.3±2.7 (SD) | 200.3±60.3 (SD) | 3550.8 | 0-t | Publications |