Intervention Studies for the metabolite Naringenin-glucuronide with food phytochemical Naringenin
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Naringenin | Naringenin-glucuronide | Human | Plasma | Host metabolism | 500 g Tomato/ 70 kg Bw | food | 41 | Healthy; 19M; 21F; Age= 28 ± 11 ; BMI= 23.3 ±3.8 Kg/m² | 3.4x10^-5 g flavanones ( 3.4x10-4 g naringenin/ kg BW; 6.14x10-7g naringenin-glucoside/ kg BW ) g/Kg bw | Single | 2.1±1.9 (SD) | 53.3±64.1 (SD) | 109.1 | 0-24h | Publications | ||||||
| Naringenin | Naringenin-glucuronide | Human | Plasma | Host metabolism | 250 g tomato sauce /70 kg Bw | food | 41 | Healthy; 19M; 21F; Age= 28 ± 11 ; BMI= 23.3 ±3.8 Kg/m² | 2.4x10-5g flavanones/kg BW ( 2.3*10^-5 g naringenin/ kg BW ; 9,28*10-7g naringenin-glucoside/ kg BW) g/Kg bw | Single | 0.8±0.4 (SD) | 130.7±80.9 (SD) | 173.1 | 0-24h | Publications | ||||||
| Naringenin | Naringenin-glucuronide | Human | Plasma and Urine | Host metabolism | 500 g of tomato | food | 8 | Healthy; 4M;4F; Age=27-46; BMI=23 ±0.93 kg/m² | 0.252 of naringenin mg | Single | 2.17±1.01 (SD) | 17.4±3.8 (SD) | 5330 | 0-∞ | 490.5 nmol (SD) (0-24h) | Publications | |||||
| Naringenin | Naringenin-glucuronide | Human | Plasma and Urine | Host metabolism | 250g of tomato sauce | food | 8 | Healthy; 4M;4F; Age=27-46; BMI=23 ±0.93 kg/m² | 0.868 mg of flavanones : [Naringenin] =0.8465 mg [Naringenin-7-glucoside] = 0.054 mg | Single | 0.64±0.09 (SD) | 427.9±59 (SD) | 49783 | 0-∞ | 5127 nmol (SD) (0-24h) | Publications | |||||
| Naringenin | Naringenin-glucuronide | Human | Plasma | Host metabolism | 250 g tomato sauce /70 kg Bw | food | 41 | Healthy; 19M; 21F; Age= 28 ± 11 ; BMI= 23.3 ±3.8 Kg/m² | 2.4x10-5g flavanones/kg BW ( 2.3*10^-5 g naringenin/ kg BW ; 9,28*10-7g naringenin-glucoside/ kg BW) g/Kg bw | Single | 0.8±0.4 (SD) | 130.7±80.9 (SD) | 173.1 | 0-24h | Publications | ||||||
| Naringenin | Naringenin-glucuronide | Human | Plasma; Urine | Host metabolism | 250g of tomato sauce | food | 8 | Healthy; 4M;4F; Age=27-46; BMI=23 ±0.93 kg/m² | 0.868 mg of flavanones : [Naringenin] =0.8465 mg [Naringenin-7-glucoside] = 0.054 mg | Single | 0,64±0,09 (SD) | 427,9±59 (SD) | 49783 | 0-∞ | 5127±1331,5 nmol (SD) (0-24h) | Publications | |||||
| Naringenin | Naringenin-glucuronide | Human | Plasma; Urine | Host metabolism | 500 g of tomato | food | 8 | Healthy; 4M;4F; Age=27-46; BMI=23 ±0.93 kg/m² | 0.252 of naringenin mg | Single | 2,17±1,01 (SD) | 17,4±3,8 (SD) | 5330 | 0-∞ | 490.5±116,5 nmol (SD) (0-24h) | Publications | |||||
| Naringenin | Naringenin-glucuronide | Human | Plasma | Host metabolism | 500 g Tomato/ 70 kg Bw | food | 41 | Healthy; 19M; 21F; Age= 28 ± 11 ; BMI= 23.3 ±3.8 Kg/m² | 3.4x10^-5 g flavanones ( 3.4x10-4 g naringenin/ kg BW; 6.14x10-7g naringenin-glucoside/ kg BW ) g/Kg bw | Single | 2.1±1.9 (SD) | 53.3±64.1 (SD) | 109.1 | 0-24h | Publications |