Intervention Studies for the metabolite Glycyrrhetinic acid with food phytochemical Glycyrrhetinic acid
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Glycyrrhetinic acid | Glycyrrhetinic acid | Human | Plasma | Unchanged | 18-β-Glycyrrhetinic acid capsules | pure compound | 6 | Healthy; M; Age= 29 ±2 ; BMI=21.76 kg/m² | 500 mg | single | 3.1±0.3 (SEM) | 4.5±0.9 (SEM) | 19.8 | 0-12h | 2.28±0.28 (SEM) | N.D | N.D | Publications | |||
| Glycyrrhetinic acid | Glycyrrhetinic acid | Human | Plasma | Unchanged | 18-β-Glycyrrhetinic acid capsules | pure compound | 6 | Healthy; M; Age= 29 ±2 ; BMI=21.76 kg/m² | 1000 mg | single | 3.2±0.3 (SEM) | 7±1.7 (SEM) | 40 | 0-24h | 2.24±0.7 (SEM) | N.D | N.D | Publications | |||
| Glycyrrhetinic acid | Glycyrrhetinic acid | Human | Plasma; Urine | Unchanged | 18-β-Glycyrrhetinic acid capsules | pure compound | 6 | Healthy; M; Age= 29 ±2 ; BMI=21.76 kg/m² | 1500 mg | single | 4.3±0.5 (SEM) | 9±2.6 (SEM) | 65.2 | 0-48h | 1.81±0.45 (SEM) | 0.07±0.02 (SEM) | 1.07±0.34 (SEM) | Publications |