Intervention Studies for the metabolite (+)-Catechin with food phytochemical (+)-Catechin
Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
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(+)-Catechin | (+)-Catechin | Human | Urine | Unchanged | Tablets | Extract | 11 | Healthy; 9 F; 2 M; Age=28±6 y; BMI=21.8±1.6 kg/m2 | 9972 µmol | Multiple | 4 weeks (6 doses daily) | 0,01103088648 | 1.1±0,2 µmol (SEM) ((0-24h)) | Publications | |||||||
(+)-Catechin | (+)-Catechin | Human | Plasma | Unchanged | 330 mL of drink | Extract | 12 | Healthy; 12 M; Age=21±2 y; BMI=24.2±1.9 kg/m2 | 1118.4 mg | Multiple | 1 day (1 dose morning + 1 dose evening) | 0,5±0,1 (SD) | 61 | (0-3h) | Publications | ||||||
(+)-Catechin | (+)-Catechin | Human | Plasma | Unchanged | 330 mL of drink | Extract | 13 | Healthy; 13 M; Age=22±5 y; BMI=24.3±3.0 kg/m2 | 1118.4 mg | Multiple | 7 days (1 dose morning + 1 dose evening) | 0,6±0,2 (SD) | 38 | (0-3h) | Publications | ||||||
(+)-Catechin | (+)-Catechin | Human | Urine | Unchanged | 120 mL of Cabernet Sauvignon | Food | 9 | Healthy; 5 M; 4 F; Age=29±3 y | 120 µmol | Single | 0,008333333333 | 0.01±0 µmol (SEM) ((0-8h)) | Publications | ||||||||
(+)-Catechin | (+)-Catechin | Human | Urine | Unchanged | 120 mL of de-alcoholized Cabernet Sauvignon | Food | 9 | Healthy; 5 M; 4 F; Age=29±3 y | 120 µmol | Single | 0,008333333333 | 0.01±0,01 µmol (SEM) ((0-8h)) | Publications |