Intervention Studies for the metabolite (Epi)catechin O-glucuronide with food phytochemical Cocoa Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cocoa Flavan-3-ols | (Epi)catechin O-glucuronide | Human | Plasma | Host metabolism | cocoa-based products containing coffee | Food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 15,6 µmol | Multiple | 1 month (twice daily) | 2,5±0,3 (SEM) | 85,6±7 (SEM) | 822,3 | (0-24h) | Publications | |||||
| Cocoa Flavan-3-ols | (Epi)catechin O-glucuronide | Human | Plasma; Urine | Host metabolism | cocoa-based products containing coffee | Food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 15,6 µmol | Multiple | 1 month (twice daily) | 1,5±0,4 (SEM) | 136,2±18,6 (SEM) | 997,6 | (0-24h) | 15,8974359 | 2.48±0,24 µmol (SEM) (h)) | Publications |