Intervention Studies for the metabolite Homovanillic acid with food phytochemical Cocoa Flavan-3-ols

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	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications

	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications
	Cocoa Flavan-3-ols		Homovanillic acid	Human	Urine	Host-gut microbiota co-metabolite	15 g of cocoa + 200 mL of milk	Food	13	Healthy; 3 M; 10 F; Age M=26.67±3.21 y; BMI M=22.47±2.97 kg/m2. Age F=32.60±9.85 y. BMI F=23.36±3.73 kg/m2	68.2 µmol	Single							0,5835777126	0.398±0,118 µmol (SD) ((0-24h))	Publications
	Cocoa Flavan-3-ols		Homovanillic acid	Human	Urine	Host-gut microbiota co-metabolite	25 g of flavanol-rich cocoa + 200 mL of milk	Food	13	Healthy; 3 M; 10 F; Age M=26.67±3.21 y; BMI M=22.47±2.97 kg/m2. Age F=32.60±9.85 y. BMI F=23.36±3.73 kg/m2	235.1 µmol	Single							0,2756273926	0.648±0,178 µmol (SD) ((0-24h))	Publications

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