Intervention Studies for the metabolite (−)-Epicatechin-sulfate with food phytochemical Cocoa Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cocoa Flavan-3-ols | (−)-Epicatechin-sulfate | Human | Urine | Host metabolism | 40 g cocoa powder + 250 mL whole milk | Food | 21 | Healthy; 9 F; 12 M; Age=25±7; BMI=21.59±2.1 kg/m2 | 62.1 mg | Single | 0,08194213506 | 0.13 µmol ((0-24h)) | Publications | ||||||||
| Cocoa Flavan-3-ols | (−)-Epicatechin-sulfate | Human | Urine | Host metabolism | 40 g cocoa powder + 250 mL whole milk | Food | 21 | Healthy; 9 F; 12 M; Age=25±7; BMI=21.59±2.1 kg/m2 | 62.1 mg | Single | 0,296873626 | 0.50 µmol ((0-24h)) | Publications | ||||||||
| Cocoa Flavan-3-ols | (−)-Epicatechin-sulfate | Human | Urine | Host metabolism | 40 g cocoa powder+ 250 mL whole milk | Food | 21 | Healthy; 9 F; 12 M; Age=25±7; BMI=21.59±2.1 kg/m2 | 62.1 mg | Single | 0,1306091622 | 0.22 µmol ((0-24h)) | Publications | ||||||||
| Cocoa Flavan-3-ols | (−)-Epicatechin-sulfate | Human | Urine | Host metabolism | 40 g cocoa powder + 250 mL water | Food | 21 | Healthy; 9 F; 12 M; Age=25±7; BMI=21.59±2.1 kg/m2 | 62.1 mg | Single | 0,1112978573 | 0.18 µmol ((0-24h)) | Publications | ||||||||
| Cocoa Flavan-3-ols | (−)-Epicatechin-sulfate | Human | Urine | Host metabolism | 40 g of cocoa powder + 250 mL water | Food | 21 | Healthy; 9 F; 12 M; Age=25±7; BMI=21.59±2.1 kg/m2 | 62.1 mg | Single | 0,4081238795 | 0.69 µmol ((0-24h)) | Publications | ||||||||
| Cocoa Flavan-3-ols | (−)-Epicatechin-sulfate | Human | Urine | Host metabolism | 40 g of cocoa powder + 250 mL water | Food | 21 | Healthy; 9 F; 12 M; Age=25±7; BMI=21.59±2.1 kg/m2 | 62.1 mg | Single | 0,01010788924 | 0.01 µmol ((0-24h)) | Publications |