Intervention Studies for the metabolite (Epi)catechin O-sulfate with food phytochemical Cocoa Flavan-3-ols
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cocoa Flavan-3-ols | (Epi)catechin O-sulfate | Human | Plasma; Urine | Host metabolism | 250 mL of hot milk + 10 g cocoa powder | Food | 9 | Healthy; Age=20-43; BMI=24.7±2.7 kg/m2 | 45 µmol | Single | 1,3±0,2 (SEM) | 77±14 (SEM) | 135 | (0-8h) | 2,00±0,2 (SEM) | 3,586666667 | 1614±135 nmol (SEM) ((0-24h)) | Publications | |||
| Cocoa Flavan-3-ols | (Epi)catechin O-sulfate | Human | Plasma; Urine | Host metabolism | 250 mL of water + 10 g cocoa powder | Food | 9 | Healthy; Age=20-43; BMI=24.7±2.7 kg/m2 | 45 µmol | Single | 1,4±0,2 (SEM) | 83±8 (SEM) | 173 | (0-8h) | 1,50±0,1 (SEM) | 5,406666667 | 2433±304 nmol (SEM) ((0-24h)) | Publications | |||
| Cocoa Flavan-3-ols | (Epi)catechin O-sulfate | Human | Urine | Host metabolism | 250 mL of hot milk + 10 g cocoa powder | Food | 9 | Healthy; Age=20-43; BMI=24.7±2.7 kg/m2 | 45 µmol | Single | 2,244444444 | 1010±104 nmol (SEM) ((0-24h)) | Publications | ||||||||
| Cocoa Flavan-3-ols | (Epi)catechin O-sulfate | Human | Urine | Host metabolism | 250 mL of water + 10 g cocoa powder | Food | 9 | Healthy; Age=20-43; BMI=24.7±2.7 kg/m2 | 45 µmol | Single | 3,911111111 | 1760±121 nmol (SEM) ((0-24h)) | Publications |