Intervention Studies for the metabolite (-)-Epicatechin 3'-O-sulfate with food phytochemical Cocoa Flavan-3-ols

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	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications

	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications
	Cocoa Flavan-3-ols		(-)-Epicatechin 3'-O-sulfate	Human	Plasma	Host metabolism	500 mL of cocoa powder drink	Food	20	Healthy; 20 M; Caucasians; Age=26±6; BMI=24±2 kg/m2	400 mg	Single		1,8±0,2 (SEM)	98±12 (SEM)	264	(0-6h)	1,20±0,1 (SEM)			Publications
	Cocoa Flavan-3-ols		(-)-Epicatechin 3'-O-sulfate	Human	Plasma	Host metabolism	500 mL of cocoa powder drink	Food	20	Healthy; 20 M; Caucasians; Age=70±4; BMI=27±3 kg/m2	400 mg	Single		1,7±0,2 (SEM)	125±13 (SEM)	365	(0-6h)	2,20±0,2 (SEM)			Publications
	Cocoa Flavan-3-ols		(-)-Epicatechin 3'-O-sulfate	Human	Plasma	Host metabolism	500 mL of cocoa powder drink	Food	20	Healthy; 20 M; Caucasians; Age=26±6; BMI=24±2 kg/m2	800 mg	Single		1,5±0,1 (SEM)	251±20 (SEM)	682	(0-6h)	1,40±0,1 (SEM)			Publications
	Cocoa Flavan-3-ols		(-)-Epicatechin 3'-O-sulfate	Human	Plasma	Host metabolism	500 mL of cocoa powder drink	Food	20	Healthy; 20 M; Caucasians; Age=70±4; BMI=27±3 kg/m2	800 mg	Single		1,7±0,1 (SEM)	212±13 (SEM)	654	(0-6h)	2,00±0,2 (SEM)			Publications

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