Intervention Studies for the metabolite 3-Methoxy-4-hydroxyphenylhydracrylic acid with food phytochemical Orange flavanones
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Orange flavanones | 3-Methoxy-4-hydroxyphenylhydracrylic acid | Human | Urine | Host-gut microbiota co-metabolite | 250 ml of orange juice enriched with 131µmol of hesperetin-7-rutinoside | food | 5 | Healthy;Age=21-50; BMI=19.9-27.2kg/m² | 168µmol of hesperetin-7-o-rutinoside and 12µmol of naringenin-7-o-rutinoside | Single | 24h | 25.9±11,4 µmol (0-24h) | Publications | ||||||||
| Orange flavanones | 3-Methoxy-4-hydroxyphenylhydracrylic acid | Human | Urine | Host-gut microbiota co-metabolite | 250 ml of orange juice enriched with 131µmol of hesperetin-7-rutinoside and 150mL of natural yoghurt | food | 5 | Healthy;Age=21-50; BMI=19.9-27.2kg/m² | 168µmol of hesperetin-7-o-rutinoside and 12µmol of naringenin-7-o-rutinoside | Single | 24h | 2.2±1,1 µmol (0-24h) | Publications |