Intervention Studies for the metabolite Dihydroferulic acid-4'-O-glucuronide with food phytochemical Ferulic acid
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ferulic acid | Dihydroferulic acid-4'-O-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 94 g of wheat bread enriched in aleurone fraction (6% w/w of aleurone) | Food | 15 | Healthy; 8 M; 7 F; Age=26±4 y; BMI=21±3 kg/m2 | 221,65 µmol | Single | 1,94 | 4.3µmol(0-48h)±4,9 (SD) (4.3µmol(0-48h)) | Publications | ||||||||
| Ferulic acid | Dihydroferulic acid-4'-O-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 190 g of bread enriched in aleurone fraction (6% w/w of aleurone) | Food | 15 | Healthy; 8 M; 7 F; Age=26±4 y; BMI=21±3 kg/m2 | 448,45 µmol | Single | 1,20 | 5.4µmol(0-48h)±3,9 (SD) (5.4µmol(0-48h)) | Publications | ||||||||
| Ferulic acid | Dihydroferulic acid-4'-O-glucuronide | Human | Urine | Host-gut microbiota co-metabolite | 94 g of wholegrain bread | Food | 15 | Healthy; 8 M; 7 F; Age=26±4 y; BMI=21±3 kg/m2 | 448,45 µmol | Single | 0,96 | 4.3µmol(0-48h)±3,9 (SD) (4.3µmol(0-48h)) | Publications |