Intervention Studies for the metabolite caffeic acid-4-O-sulfate with food phytochemical Coffee hydroxycinnamates
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coffee hydroxycinnamates | caffeic acid-4-O-sulfate | Human | Urine | Host-gut microbiota co-metabolite | Coffee (200 mL) containing 3.4 g of powdered instant coffee | food | 11 | Healthy; 8 M; 3 F; age=19-35 y; BMI= 24.3±2.3 kg/m2 | 412,50 µmol | Single | 0.1 ± 0 (SEM) | 0.6µmol(0-24h)±0,1 (SEM) (0.6µmol(0-24h)) | Publications |