Intervention Studies for the metabolite 3-Feruloylquinic acid with food phytochemical 3-Feruloylquinic acid
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Plasma | Unchanged | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 778,43 µmol | Single | 1 | 10,79±0,93 (SEM) | Publications | ||||||||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Plasma | Unchanged | 3.6 g of ground coffee + 50 mL water | food | 15 | Healthy; Age=26.3 ± 1.6 y; BMI=23.5 ± 0.5 kg/m2 | 214,15 µmol | Single | 1 | 11,61±1,03 (SEM) | Publications | ||||||||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Plasma | Unchanged | 200 mL of coffee + 2 bread rolls + honey | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 1,15 | 8 | 64 | (0-15h) | Publications | ||||||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Plasma | Unchanged | 200 mL of instant coffee beverage | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 0,47 | 11 | 291 | (0-15h) | Publications | ||||||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Plasma | Unchanged | 200 mL of coffee + 1 bread roll + peanut butter | food | 14 | Healthy; 7 M; 7 F; Age=29.36±8.06 y; BMI=22.95±1.72 kg/m2; Caucasians | 48,03 µmol | Single | 1,15 | 10 | 317 | (0-15h) | Publications | ||||||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 0,5±(0.5;1.0) (IR) | 16±(13;17) (IR) | 25 | (0-24h) | 0,9±(0.7;1.1) (IR) | 5,10 | 1.2µmol(0-24h)±(0.8;1.4) (IR) (1.2µmol(0-24h)) | Publications | |||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 635,00 µmol | Single | 1±(0.5;1.0) (IR) | 43±(29;46) (IR) | 78 | (0-24h) | 1±(0.7;1.0) (IR) | 6,20 | 1.6µmol(0-24h)±(1.3;2.3) (IR) (1.6µmol(0-24h)) | Publications | |||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of instant coffee beverage | food | 11 | healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 795,00 µmol | Single | 0,5±(0.5;1.3) (IR) | 13±(10;16) (IR) | 24 | (0-24h) | 1±(0.8;1.3) (IR) | 4,40 | 0.7µmol(0-24h)±(0.6;0.9) (IR) (0.7µmol(0-24h)) | Publications | |||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Plasma; Urine | Unchanged | 200 mL of coffee (3.4 g of instant powder) | food | 11 | Healthy; 8 M; 3 F; Age=19-35 y; BMI=24.3±2.3 kg/m2 | 412,00 µmol | Single | 0±0,1 (SEM) | 16±2 (SEM) | 30,5 | (0-24h) | 0,9±0,1 (SEM) | 0,29 | 1.2µmol(2-24h)±0,1 (SEM) (1.2µmol(2-24h)) | Publications | |||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Urine | Unchanged | 250 mL of coffee (3.5 g of green-roasted coffee) | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 760.6 μmol | Single | 0,12 | 0.9µmol(0-24h)±0,2 (SD) (0.9µmol(0-24h)) | Publications | ||||||||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Urine | Unchanged | 1 cup of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 204,90 µmol | Multiple | 1 month (1 daily dose) | 0,43 | 0.88µmol(0-24h)±0,08 (SEM) (0.88µmol(0-24h)) | Publications | |||||||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Urine | Unchanged | 3 cups of coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 614,60 µmol | Multiple | 1 month (3 dose daily) | 0,45 | 2.75µmol(0-24h)±0,28 (SEM) (2.75µmol(0-24h)) | Publications | |||||||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Urine | Unchanged | 1 cup of coffee + 2 cocoa products containing coffee | food | 21 | Healthy; 11 F; 10 M; Age=22.9 ± 0.5 y; BMI: 22.3 ± 1.7 kg/m2 | 296,00 µmol | Multiple | 1 month (2 dose daily) | 0,35 | 1.05µmol(0-24h)±0,11 (SEM) (1.05µmol(0-24h)) | Publications | |||||||
| 3-Feruloylquinic acid | 3-Feruloylquinic acid | Human | Urine | Unchanged | 4.91 g of yerba mate in 250 mL water | food | 12 | Healthy; 7 M (Age=27.86±3.48 y; BMI=23.42±2.52 kg/m2); 5 F (Age=28.88±3.56 y; BMI=22.43±3.33 kg/m2) | 1118,00 µmol | Single | 0,03 | 0.383µmol(0-24h)±0,087 (SD) (0.383µmol(0-24h)) | Publications |