Intervention Studies for the metabolite Rosmarinic acid with food phytochemical Rosmarinic acid
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rosmarinic acid | Rosmarinic acid | Human | Serum | Unchanged | Melissa Officinalis capsules | extract | 6 | 694,44 µmol | Single | 0,75±(0.00;2.00) (IR) | 30,68±12,88 (SEM) | 31,25 | (0-48h) | Publications | |||||||
| Rosmarinic acid | Rosmarinic acid | Human | Serum | Unchanged | Melissa Officinalis capsules | extract | 6 | 1388,89 µmol | Single | 1±(1.00;3.00) (IR) | 124,03±39,13 (SEM) | 228,77 | (0-48h) | Publications | |||||||
| Rosmarinic acid | Rosmarinic acid | Human | Serum | Unchanged | Melissa Officinalis capsules | extract | 6 | 1388,89 µmol | Single | 2,5±(0.00;3.00) (IR) | 85,95±34,97 (SEM) | 438,15 | (0-48h) | Publications | |||||||
| Rosmarinic acid | Rosmarinic acid | Human | Urine | Unchanged | 100 mL of water + 10 g of dried rosemary leaves | food | 12 | Healthy; 8 F (Age=36±10 y; BMI=24±2 kg/m2); 4 M (Age=24±3 y; BMI=23±2 kg/m2) | 1074,26 µmol | Single | 0,00 | 0.03µmol(0-24h)±0,01 (SD) (0.03µmol(0-24h)) | Publications |