Intervention Studies for the metabolite 3'-Hydroxyphenylacetic acid with food phytochemical Orange flavanones
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Publications | |||||||||||||||||||
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Human | Plasma | Gut microbiota metabolite | 500 mL Orange juice (Tropicana with bits) | food | 10 | Endurance trained; M; Age= 31.8 ± 5.7; BMI= 21.7 ± 1.8 kg/m2 | 330 μmol flavanones µmol | Single | 3.1±0.2 (SEM) | 34±2 (SEM) | 175 | 0-8 h | Publications | ||||||
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Human | Urine | Gut microbiota metabolite | 548 mL Orange juice (Tropicana with bits) | food | 10 | Endurance-trained; M; BMI= 21.7 ± 0.6 kg/m²; stoping training for 7 days | 330 µmol flavanones | Single | 0.43 (SEM) | 1.7±0.14 µmol (SEM) (0-24h) | Publications | ||||||||
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Human | Plasma; Urine | Gut microbiota metabolite | 500 ml of orange juice | food | 12 | Healthy; M; Age=31.8±5.7; BMI=21.7±1.8kg/m² | 250µmol of hesperetin derivatives and 75µmol of naringenin derivatives | Single | 24h | Publications | |||||||||
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Human | Urine | Gut microbiota metabolite | 250 ml of orange juice enriched with 131µmol of hesperetin-7-rutinoside | food | 5 | Healthy;Age=21-50; BMI=19.9-27.2kg/m² | 168µmol of hesperetin-7-o-rutinoside and 12µmol of naringenin-7-o-rutinoside | Single | 24h | 4.05 | 7.3 µmol (0-24h) | Publications | |||||||
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Human | Urine | Gut microbiota metabolite | 250 ml of orange juice enriched with 131µmol of hesperetin-7-rutinoside and 150mL of natural yoghurt | food | 5 | Healthy;Age=21-50; BMI=19.9-27.2kg/m² | 168µmol of hesperetin-7-o-rutinoside and 12µmol of naringenin-7-o-rutinoside | Single | 24h | 2.16 | 3.9 µmol (0-24h) | Publications | |||||||
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Human | Plasma | Gut microbiota metabolite | 500 mL Orange juice (Tropicana with bits) | food | 10 | Endurance trained; M; Age= 31.8 ± 5.7; BMI= 21.7 ± 1.8 kg/m2 | 330 μmol flavanones µmol | Single | 3.1±0.2 (SEM) | 34±2 (SEM) | 175 | 0-8 h | Publications | ||||||
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Human | Urine | Gut microbiota metabolite | 250 ml of orange juice enriched with 131µmol of hesperetin-7-rutinoside | food | 5 | Healthy;Age=21-50; BMI=19.9-27.2kg/m² | 168µmol of hesperetin-7-o-rutinoside and 12µmol of naringenin-7-o-rutinoside | Single | 24h | 4,05 | 7.3±3 µmol (0-24h) | Publications | |||||||
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Human | Urine | Gut microbiota metabolite | 250 ml of orange juice enriched with 131µmol of hesperetin-7-rutinoside and 150mL of natural yoghurt | food | 5 | Healthy;Age=21-50; BMI=19.9-27.2kg/m² | 168µmol of hesperetin-7-o-rutinoside and 12µmol of naringenin-7-o-rutinoside | Single | 24h | 2,16 | 3.9±2,6 µmol (0-24h) | Publications | |||||||
| Orange flavanones | 3'-Hydroxyphenylacetic acid | Human | Urine | Gut microbiota metabolite | 548 mL Orange juice (Tropicana with bits) | food | 10 | Endurance-trained; M; BMI= 21.7 ± 0.6 kg/m²; stoping training for 7 days | 330 µmol flavanones | Single | 0.43±0.14 (SEM) | 1.7±0.6 µmol (SEM) (0-24h) | Publications |