Intervention Studies for the metabolite 3-(3'-hydroxy-4'-methoxyphenyl)propanoic acid with food phytochemical Orange flavanones
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Orange flavanones | 3-(3'-hydroxy-4'-methoxyphenyl)propanoic acid | Human | Urine | Host-gut microbiota co-metabolite | 400 g orange fruit | food | 11 | Healthy; Age= 28; BMI= 23.2±1.8 kg/m² | 1477 µmol | Single | 24 hours | 10.8±0.74 µmol (SEM) (0-24h) | Publications | ||||||||
| Orange flavanones | 3-(3'-hydroxy-4'-methoxyphenyl)propanoic acid | Human | Urine | Host-gut microbiota co-metabolite | 719 g pasteurized orange juice | food | 11 | Healthy; Age=28; BMI =23.2±1.8 kg/m² | 636 µmol | Single | 24 hours | 6.53µmol±1.026 0-24h (SEM) (0-24h) | Publications | ||||||||
| Orange flavanones | 3-(3'-hydroxy-4'-methoxyphenyl)propanoic acid | Human | Urine | Gut microbiota metabolite | 250 ml pulp enriched orange juice | food | 8 | Healthy; Age=23-60;BMI=23.9- 37.2 kg/m² | 537 µmol flavanones [naringenin-7-O-rutinoside (114 µmol), hesperetin-7-O-rutinoside (329 µmol), didymin(19 µmol), naringenin-7-O-rutinoside-4'-O-glucoside (51 µmol); hesperetin-7-O-rutinoside-3'-Oglucoside (19 µmol), eriodictyol-7-O-rutinoside (5 µmol)] | Single | 24h | 4.7µmol±0.87 0-24h (0-24h) | Publications | ||||||||
| Orange flavanones | 3-(3'-hydroxy-4'-methoxyphenyl)propanoic acid | Human | Urine | Gut microbiota metabolite | 250 ml pulp enriched orange juice | food | 8 | Healthy; Age=23-60;BMI=23.9- 37.2 kg/m² | 537 µmol flavanones [naringenin-7-O-rutinoside (114 µmol), hesperetin-7-O-rutinoside (329 µmol), didymin(19 µmol), naringenin-7-O-rutinoside-4'-O-glucoside (51 µmol); hesperetin-7-O-rutinoside-3'-Oglucoside (19 µmol), eriodictyol-7-O-rutinoside (5 µmol)] | Single | 24h | 4.7µmol±0,8 0-24h (0-24h) | Publications | ||||||||
| Orange flavanones | 3-(3'-hydroxy-4'-methoxyphenyl)propanoic acid | Human | Urine | Host-gut microbiota co-metabolite | 400 g orange fruit | food | 11 | Healthy; Age= 28; BMI= 23.2±1.8 kg/m² | 1477 µmol | Single | 24 hours | 10.8±3,6 µmol (SEM) (0-24h) | Publications | ||||||||
| Orange flavanones | 3-(3'-hydroxy-4'-methoxyphenyl)propanoic acid | Human | Urine | Host-gut microbiota co-metabolite | 719 g pasteurized orange juice | food | 11 | Healthy; Age=28; BMI =23.2±1.8 kg/m² | 636 µmol | Single | 24 hours | 6.53µmol±1,9 0-24h (SEM) (0-24h) | Publications |