Intervention Studies for the metabolite Naringenin-4'-sulfate with food phytochemical Orange flavanones
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Orange flavanones | Naringenin-4'-sulfate | Human | Plasma | Host metabolism | 500 mL Orange juice (Tropicana with bits) | food | 10 | Endurance trained; M; Age= 31.8 ± 5.7; BMI= 21.7 ± 1.8 kg/m2 | 330 μmol flavanones µmol | Single | 5.4±0.4 (SEM) | 11±7 (SEM) | 39 | 0-8 h | Publications | ||||||
| Orange flavanones | Naringenin-4'-sulfate | Human | Urine | Host metabolism | 250 ml of orange juice | food | 4 | Healthy; 2M;2F; Age=23-30; BMI= 19.9-23.5kg/m² | 31.39 μmol | Single | 0.17 (SD) | 51.8±0.0002707868748 nmol (SD) (0-24h) | Publications | ||||||||
| Orange flavanones | Naringenin-4'-sulfate | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 500 ml of orange juice | food | 12 | Healthy, M, Age=31.8±5.7; BMI=21.7±1.8kg/m² | 250µmol of hesperetin derivatives and 75µmol of naringenin derivatives | Single | 24h | Publications | |||||||||
| Orange flavanones | Naringenin-4'-sulfate | Human | Plasma | Host metabolism | 500 mL Orange juice (Tropicana with bits) | food | 10 | Endurance trained; M; Age= 31.8 ± 5.7; BMI= 21.7 ± 1.8 kg/m2 | 330 μmol flavanones µmol | Single | 5.4±0.4 (SEM) | 11±7 (SEM) | 39 | 0-8 h | Publications | ||||||
| Orange flavanones | Naringenin-4'-sulfate | Human | Urine | Host metabolism | 250 ml of orange juice | food | 4 | Healthy; 2M;2F; Age=23-30; BMI= 19.9-23.5kg/m² | 31,39 µmol | Single | 0,1650207072±0,0002707868748 (SD) | 51.8±8,5 nmol (SD) (0-24h) | Publications |