Intervention Studies for the metabolite Dihydroferulic acid-4'-O-glucuronide with food phytochemical Orange flavanones
| Food Phytochemical | Metabolite | Species | Biofluids | Origin | Dietary Source Description | Dietary Source Classification | Total Number of Subjects | Description of Population | Ingested Amount | Single/Multiple Dose | Duration of the Study | Tmax (h) | Cmax (nM) | AUC (nM/h) | Time covered by AUC (h) | t 1/2 (h) | % of 24h Urinary Excretion | Excreted Amount & Time Interval | Publications | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Orange flavanones | Dihydroferulic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 500 mL Orange juice (Tropicana with bits) | food | 10 | Endurance trained; M; Age= 31.8 ± 5.7; BMI= 21.7 ± 1.8 kg/m2 | 330 μmol flavanones µmol | Single | 6.2±0.2 (SEM) | 4.7±0.3 (SEM) | 14 | 0-8 h | Publications | ||||||
| Orange flavanones | Dihydroferulic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 500 mL orange Juice: Citrus sinensis | food | 9 | Healthy;2M; 7F; Age= 21 -25; BMI= 21.1 ± 2.4 kg/m² | 502.7± 20.7 µmol flavanones | Single | 5.8±0.5 (SEM) | 39±12 (SEM) | 87 | 0-8 h | Publications | ||||||
| Orange flavanones | Dihydroferulic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 500 ml fermented orange Juice | food | 9 | Healthy;2M; 7F; Age= 21 -25; BMI= 21.1 ± 2.4 kg/m² | 667.2±31.6 µmol flavanones | Single | 6.1±0.5 (SEM) | 52±21 (SEM) | 151 | 0-8 h | Publications | ||||||
| Orange flavanones | Dihydroferulic acid-4'-O-glucuronide | Human | Plasma and Urine | Host-gut microbiota co-metabolite | 500 ml of orange juice | food | 12 | Healthy; M; Age=31.8±5.7; BMI=21.7±1.8kg/m² | 250µmol of hesperetin derivatives and 75µmol of naringenin derivatives | Single | 24h | Publications | |||||||||
| Orange flavanones | Dihydroferulic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 500 mL Orange juice (Tropicana with bits) | food | 10 | Endurance trained; M; Age= 31.8 ± 5.7; BMI= 21.7 ± 1.8 kg/m2 | 330 μmol flavanones µmol | Single | 6.2±0.2 (SEM) | 4.7±0.3 (SEM) | 14 | 0-8 h | Publications | ||||||
| Orange flavanones | Dihydroferulic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 500 ml fermented orange Juice | food | 9 | Healthy;2M; 7F; Age= 21 -25; BMI= 21.1 ± 2.4 kg/m² | 667.2±31.6 µmol flavanones | Single | 6.1±0.5 (SEM) | 52±21 (SEM) | 151 | 0-8 h | Publications | ||||||
| Orange flavanones | Dihydroferulic acid-4'-O-glucuronide | Human | Plasma | Host-gut microbiota co-metabolite | 500 mL orange Juice: Citrus sinensis | food | 9 | Healthy;2M; 7F; Age= 21 -25; BMI= 21.1 ± 2.4 kg/m² | 502.7± 20.7 µmol flavanones | Single | 5.8±0.5 (SEM) | 39±12 (SEM) | 87 | 0-8 h | Publications | ||||||
| Orange flavanones | Dihydroferulic acid-4'-O-glucuronide | Human | Plasma; Urine | Host-gut microbiota co-metabolite | 500 ml of orange juice | food | 12 | Healthy; M; Age=31.8±5.7; BMI=21.7±1.8kg/m² | 250µmol of hesperetin derivatives and 75µmol of naringenin derivatives | Single | 24h | Publications |