Intervention Studies for the metabolite 3',4'-Dihydroxyphenylacetic acid with food phytochemical Orange flavanones

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	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications

	Food Phytochemical		Metabolite	Species	Biofluids	Origin	Dietary Source Description	Dietary Source Classification	Total Number of Subjects	Description of Population	Ingested Amount	Single/Multiple Dose	Duration of the Study	Tmax (h)	Cmax (nM)	AUC (nM/h)	Time covered by AUC (h)	t 1/2 (h)	% of 24h Urinary Excretion	Excreted Amount & Time Interval	Publications
	Orange flavanones		3',4'-Dihydroxyphenylacetic acid	Human	Urine	Host-gut microbiota co-metabolite	551 mL Orange juice (Tropicana with bits)	food	10	Endurance-trained; M; BMI= 21.7 ± 0.6 kg/m²; performed 5-10 h endurance training per week	330 µmol flavanones	Single							0.3 (SEM)	1.1±0.1 µmol (SEM) (0-24h)	Publications
	Orange flavanones		3',4'-Dihydroxyphenylacetic acid	Human	Urine	Gut microbiota metabolite	500 ml of orange juice	food	12	Healthy; M; Age=31.8±5.7; BMI=21.7±1.8kg/m²	250µmol of hesperetin derivatives and 75µmol of naringenin derivatives	Single	24h								Publications
	Orange flavanones		3',4'-Dihydroxyphenylacetic acid	Human	Urine	Host-gut microbiota co-metabolite	551 mL Orange juice (Tropicana with bits)	food	10	Endurance-trained; M; BMI= 21.7 ± 0.6 kg/m²; performed 5-10 h endurance training per week	330 µmol flavanones	Single							0.3±0.1 (SEM)	1.1±0.4 µmol (SEM) (0-24h)	Publications

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