Dihydrocaffeic acid-3'-O-glucuronide
Showing entry for Dihydrocaffeic acid-3'-O-glucuronide
Identification
- PhytoHub ID
- PHUB001204
- Name
- Dihydrocaffeic acid-3'-O-glucuronide
- Systematic Name
- 3-(4'-hydroxyphenyl)propanoic acid-3'-glucuronide
- Synonyms
- 3-(4-hydroxyphenyl)propanoic acid-3-glucuronide
- 3-(4-hydroxyphenyl)propionic acid-3-glucuronide
- 3-(4'-Hydroxyphenyl)propionic acid-3'-O-glucuronide
- dihydrocaffeic acid-3-glucuronide
- CAS Number
- Not Available
- Average Mass
- 358.299
- Monoisotopic Mass
- 358.08999678
- Chemical Formula
- C15H18O10
- IUPAC Name
- (2R,3R,4R,5S,6R)-6-[5-(2-carboxyethyl)-2-hydroxyphenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
- InChI Key
- AELQNMHOLDHBFA-VVSAWPALSA-N
- InChI Identifier
InChI=1S/C15H18O10/c16-7-3-1-6(2-4-9(17)18)5-8(7)24-15-12(21)10(19)11(20)13(25-15)14(22)23/h1,3,5,10-13,15-16,19-21H,2,4H2,(H,17,18)(H,22,23)/t10-,11-,12+,13-,15+/m1/s1
- SMILES
O[[email protected]]1[[email protected]](O)[[email protected]@H](OC2=C(O)C=CC(CCC(O)=O)=C2)O[[email protected]]([[email protected]@H]1O)C(O)=O
- Structure
Calculated Properties
- Solubility (ALOGPS)
- 8.41e+00 g/l
- LogS (ALOGPS)
- -1.63
- LogP (ALOGPS)
- -0.09
- Hydrogen Acceptors
- 10
- Hydrogen Donors
- 6
- Rotatable Bond Count
- 6
- Polar Surface Area
- 173.98
- Refractivity
- 77.9402
- Polarizability
- 32.98813207252531
- Formal Charge
- 0
- Physiological Charge
- -2
- pKa (strongest basic)
- -3.6868279761517333
- pKa (strongest acidic)
- 3.0131597965048678
- Number of Rings
- 2
- Rule of Five
- No
- Bioavailability
- Yes
- Ghose Filter
- No
- Veber's Rule
- No
- MDDR-like Rule
- No
External Links
No external links
Taxonomy as Metabolite
- Family
- (Poly)phenol metabolites
- Class
- Phenolic acid metabolites
- Sub-class
- Phenylpropanoic acids
Taxonomy of its Precursor(s)
Precursor | Family | Class | Sub-class | |
---|---|---|---|---|
Dihydrocaffeic acid | (Poly)phenol metabolites | Phenolic acid metabolites | Phenylpropanoic acids | Show Precursor |
Caffeic acid | Polyphenols | Phenolic acids | Hydroxycinnamic acids | Show Precursor |
Orange flavanones | Polyphenols | Flavonoids | Flavanones | Show Precursor |
Classyfire Taxonomy
- Kingdom Name
- Organic compounds
- Class
- Organooxygen compounds
- Super-class
- Organic oxygen compounds
- Sub-class
- Carbohydrates and carbohydrate conjugates
- Direct Parent Name
- Phenolic glycosides
- Alternative Parent Names
- ["1-hydroxy-2-unsubstituted benzenoids", "Acetals", "Beta hydroxy acids and derivatives", "Carbonyl compounds", "Carboxylic acids", "Dicarboxylic acids and derivatives", "Hexoses", "Hydrocarbon derivatives", "O-glucuronides", "O-glycosyl compounds", "Organic oxides", "Oxacyclic compounds", "Oxanes", "Phenol ethers", "Phenoxy compounds", "Phenylpropanoic acids", "Polyols", "Pyrans", "Secondary alcohols"]
- External Descriptor Annotations
- Not Available
- Substituent Names
- ["1-hydroxy-2-unsubstituted benzenoid", "1-o-glucuronide", "3-phenylpropanoic-acid", "Acetal", "Alcohol", "Aromatic heteromonocyclic compound", "Benzenoid", "Beta-hydroxy acid", "Carbonyl group", "Carboxylic acid", "Carboxylic acid derivative", "Dicarboxylic acid or derivatives", "Glucuronic acid or derivatives", "Hexose monosaccharide", "Hydrocarbon derivative", "Hydroxy acid", "Monocyclic benzene moiety", "Monosaccharide", "O-glucuronide", "O-glycosyl compound", "Organic oxide", "Organoheterocyclic compound", "Oxacycle", "Oxane", "Phenol", "Phenol ether", "Phenolic glycoside", "Phenoxy compound", "Polyol", "Pyran", "Secondary alcohol"]
Spectra from Online Resources
No spectra information available
Food Sources
No food source information available
Food Sources of its Precursor(s)
Metabolism
Precursor | Metabolite | Species | Biofluids | Origin | TMax | CMax | Urinary Excretion | Formula | Monoisotopic mass | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrocaffeic acid | Dihydrocaffeic acid-3'-O-glucuronide | rat | urine | Not Available | Not Available | Not Available | Not Available | C15H18O10 | 358.08999678 | Publications | |||
Caffeic acid | Dihydrocaffeic acid-3'-O-glucuronide | human | plasma | host metabolism | Not Available | Not Available | Not Available | C15H18O10 | 358.08999678 | Publications | |||
Orange flavanones | Dihydrocaffeic acid-3'-O-glucuronide | Not Available | Not Available | Not Available | Not Available | Not Available | Not Available | C15H18O10 | 358.08999678 | Detailed Intervention Studies |
Inter-Individual Variations Metabolism
No data on inter-individual variations available